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NAME ___________________________ 1 BIOLOGY 205/SECTION 7 DEVELOPMENT- LILJEGREN Final Examination – April 29, 2009 Write your name at the top of each page. Read each question carefully before answering—i.e. read the instructions. In all answers, be as specific as possible , while respecting the amount of space allotted for each answer. Use of calculators and cell phones is prohibited during the exam. No regrades will be made on exams done in pencil. Be sure to sign and abide by the honor code pledge. ---------------------------------------------------------- 1.) (8 pts) It’s important to remember that proteins have specific jobs to do in the cell. For each protein below, indicate which of the following categories best describes its job: (Some categories may not be used.) a. Transcription factor e. Secreted signal b. Transmembrane receptor f. Homeodomain transcription factor c. Membrane-bound signal g. Transmembrane channel protein d. MADS-domain transcription factor h. Chromatin binding protein Polycomb _________________ Ultrabithorax __________________ MOM-2 __________________ Pax3 __________________ LET-23 __________________ APETALA3 __________________ LEAFY __________________ Delta __________________ 2.) (1 pt) One global mechanism of regulating gene expression involves the post- translational modification of __________________ proteins associated with DNA. 3.) (10 pts) We discussed how the fly body plan is specified by a cascade of genes during embryonic development. For each of the functions described below (which are NOT shown in order), name which gene category it represents , and name ONE actual gene in that category selected from the following list. Porcupine Antennapedia Raspberry Butthead Bald Fushi tarazu Mastermind Bicoid Krüppel Distalless Wingless Distorted Function Category A gene in this category Set up crude subdivisions ____________________ _____________________ Define anterior/posterior regions ____________________ _____________________ of segments Form more refined segments ____________________ _____________________ Specify segment identity ____________________ _____________________ Establish anterior/posterior axis ____________________ _____________________
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NAME ___________________________ 2 4.) (2 pts) Which organism(s) uses DNA methylation as a mechanism to regulate gene transcription? (A) Mouse (B) C. elegans Write letter(s) here _______ (C) Zebrafish (D) Drosophila (E) All of the above 5.) (2 pts) Hunchback is normally expressed in the segments of the fly embryo that will become the head. (Circle one)
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This note was uploaded on 05/26/2011 for the course BIO 205 taught by Professor Reed during the Spring '11 term at UNC.

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