2010Exam4

2010Exam4 - NAME BIOLOGY 205/SECTION 7 DEVELOPMENT...

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NAME ___________________________ 1 BIOLOGY 205/SECTION 7 DEVELOPMENT- LILJEGREN Final Examination – May 6, 2010 Write your name at the top of each page. Read each question carefully before answering—i.e. read the instructions. In all answers, be as specific as possible , while respecting the amount of space allotted for each answer. Use of calculators and cell phones is prohibited during the exam. No regrades will be made on exams done in pencil. Be sure to sign and abide by the honor code pledge. ---------------------------------------------------------- 1.) (8 pts) It’s important to remember that proteins have specific jobs to do in the cell. For each protein below, indicate which of the following categories best describes its job: (Some categories may not be used.) a. Transcription factor e. Secreted signal b. Transmembrane receptor kinase f. Homeodomain transcription factor c. Membrane-bound signal g. Transmembrane channel protein d. MADS-domain transcription factor h. Ras G-protein Hunchback _________________ Abdominal B __________________ LIN-3 __________________ PISTILLATA __________________ LET-60 __________________ Steel __________________ White (fly) __________________ White-spotting __________________ 2.) (2 pts) Which organism(s) uses genomic imprinting as a mechanism to regulate transcription of specific genes? (A) Chicken (D) Zebrafish Write letter(s) here _______ (B) Frog (E) Fruit fly (C) Mouse (F) All of the above 3.) (8 pts) We discussed how the fly body plan is specified by a cascade of genes during embryonic development. For each of the functions described below (which are NOT shown in order), name which gene category it represents , and name ONE actual gene in that category selected from the following list. Na-nu Krups Engraved Even-skipped Peccadillo Fugu sushi Nanos Bic Ultrabithorax Knirps Engrailed Lorax Function Category A gene in this category Specify segment identity ____________________ _____________________ Form more refined segments ____________________ _____________________ Set up crude subdivisions ____________________ _____________________ Establish anterior/posterior axis ____________________ _____________________
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NAME ___________________________ 2 4.) (2 pts) Based on the LIN-12/LAG-2 signaling involved in deciding anchor cell fate, what would you expect during the signaling in the fly neurogenic ectoderm? Write letter(s) here _______ (A) Cells with activated Notch would produce more Delta (B) Cells with activated Notch would produce the same amount of Notch (C) Cells with activated Notch would produce less Notch (D) Cells with activated Notch would produce less Delta (E) Cells with activated Notch would produce more Notch (F) Cells with activated Notch would produce the same amount of Delta 5.) (1 pt) In generating MyoD ‘knockout’ mice, researchers tested whether: (A) MyoD is necessary for muscle development (B) MyoD is sufficient for muscle development Write letter here _____ (C)
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This note was uploaded on 05/26/2011 for the course BIO 205 taught by Professor Reed during the Spring '11 term at UNC.

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2010Exam4 - NAME BIOLOGY 205/SECTION 7 DEVELOPMENT...

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