DBLecture1posted

DBLecture1posted - How does a fertilized egg become an...

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1 How does a fertilized egg become an animal? Clam egg and sperm
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2
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3 Developmental Biology is the study of a PROCESS whereby a single cell (the fertilized egg) divides and selectively activates expression of genes to produce a complex organism composed of many cell types . Ex ovo omnia!
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4 To form an embryo, the following (and more!) must occur: Gametes form and fuse ( Reproduction ) Cells multiply ( Growth ) Generation of Asymmetry Axis Determination (Positional information) - Anterior/Posterior (Head-Tail) - Dorsal/Ventral (Back-Front) - Left/Right Cells differentiate Structures are built from cells ( Morphogenesis ) - Animal cells organize into sheets and move - Plant cells form structures without moving What kinds of PROCESSES are required?
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5 Differentiation is a central idea of development: All cells have the same DNA, but DIFFERENT CELLS express DIFFERENT GENES
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6 Nature supports an incredible diversity of plant and animal body plans
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7 Yet all of these organisms share conserved developmental mechanisms that are evidence of their evolution from a common ancestor . Our challenge is to understand both this diversity and this unity.
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8 Developmental Biology is studied using the following TOOLS 1. Cell Biology 2. Genetics 3. Molecular Biology
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9 Let’s Review the Basics 1. The body is made of millions to billions of cells .
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