{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Lecture 3 - Cell potential and cloning

Lecture 3 - Cell potential and cloning - Cell potential...

Info icon This preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon
Cell potential, animal cloning Can any cell develop into a complete organism? How do you clone a sheep?
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Regenerating plants from a single cell
Image of page 2
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Testing the developmental potential of nuclei from differentiated cells (Needle prick can activate some eggs) (or suck out meiotic spindle with pipette) Does tadpole develop?
Image of page 4
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Copyright ©2003 by the National Academy of Sciences Gurdon, J. B. and Byrne, J. A. (2003) Proc. Natl. Acad. Sci. USA 100, 8048-8052 Fig. 2. (A) In Amphibia, nuclear transfer success declines rapidly as cells differentiate
Image of page 6
Copyright ©2003 by the National Academy of Sciences Gurdon, J. B. and Byrne, J. A. (2003) Proc. Natl. Acad. Sci. USA 100, 8048-8052 Fig. 2. (A) In Amphibia, nuclear transfer success declines rapidly as cells differentiate
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Donor nucleus Stages reached Zygote blastula, tadpole, adult Blastula blastula, tadpole, adult Tadpole intestine blastula, tadpole, adult Cultured skin cell blastula (differentiated) Success of nuclear transplant experiments
Image of page 8
Donor nucleus Stages reached Zygote blastula, tadpole, adult Blastula blastula, tadpole, adult Tadpole intestine blastula, tadpole, adult Cultured skin cell blastula Blastula from above blastula, tadpole Could some genes be missing from differentiated skin cells?
Image of page 9

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Serial nuclear transfer improves the efficiency of cloning
Image of page 10
Conclusions of nuclear transplantation experiments in amphibians: 1) Nuclei of differentiated cells have the potential to program development of many or all cells. (Therefore, the nuclei must contain all the necessary genes.)
Image of page 11

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Conclusions of nuclear transplantation experiments in amphibians:
Image of page 12
Image of page 13
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern