Lecture 6 - Signals in frog embryogenesis

Lecture 6 Signals - Signals in frog embryos How can we identify developmental signaling pathways and test their roles How do other vertebrate

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Signals in frog embryos How can we identify developmental signaling pathways and test their roles? How do other vertebrate embryos develop?
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Developmental biology jargon Cell fate – the normal future identity of a cell (muscle, skin, etc.). A fate map represents future cell fates. Specification – the process by which a cell acquires a particular fate. Specified cells could still switch to some other fate in response to perceived signals. A specification map represents the identities that cells have acquired at a particular stage. Determination – the process by which cells fix their fate stably. Determined cells do not change fate even if they receive new signals. Differentiation – the process by which cells actually change to take on a particular identity (e.g. express muscle-specific genes).
Background image of page 2
~64-cell stage late blastula gastrulation Mesoderm induction and patterning
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
What experimental results demonstrate that a particular signal induces a response?
Background image of page 4
What experimental results demonstrate that a particular signal induces a response? Location – The signal must be present in the right place and at the
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/26/2011 for the course BIO 205 taught by Professor Reed during the Spring '11 term at UNC.

Page1 / 44

Lecture 6 Signals - Signals in frog embryos How can we identify developmental signaling pathways and test their roles How do other vertebrate

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online