Lecture 11 - Self-organization, Meristems

Lecture 11 - Self-organization, Meristems - Genetic models...

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Genetic models Self-organization How do genetic approaches help to understand development? How can equivalent cells organize themselves into a pattern?
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Gene Function Phenotype
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Gene Mutant Phenotype To find out what a particular gene does during development: 1) Make a targeted mutation in the gene (e.g. a knockout mouse). 2) Examine the resulting phenotypes. 3) Deduce the gene’s function. Developmental Function
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Gene To identify genes that carry out a particular developmental process: 1) Screen for mutants in which the process is altered (i.e. with mutant phenotypes). 2) Identify the genes that have been mutated. 3) Deduce function from phenotypes. Developmental Function Mutant Phenotype
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Developmental Function Protein Biochemical Function Gene Cloned genes can be used to analyze biochemical functions involved in a developmental process Mutant Phenotype
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To understand a developmental process, figure out relations among genes and proteins affecting the process. Developmental
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This note was uploaded on 05/26/2011 for the course BIO 205 taught by Professor Reed during the Spring '11 term at UNC.

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Lecture 11 - Self-organization, Meristems - Genetic models...

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