Lecture5

Lecture5 - 01.21.11 Lecture 5: Membrane transport Ion...

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01.21.11 Lecture 5: Membrane transport
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Ion concentrations within the cell are different from those outside
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Few molecules cross the membrane by passive diffusion
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Each cell membrane transports specific molecules
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Solutes cross membranes by passive or active transport Passive transport is driven by concentration gradients & electrical forces Active transport is requires energy
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An electrochemical gradient is driven by 2 forces Concentration gradient - ions move across a membrane from high to low concentrations Voltage across the membrane High for sodium, low for potassium
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There are 3 main classes of membrane transport proteins
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Passive transport by glucose carrier protein (GLUT2) Carrier protein randomly switches between two states Glucose moves down it’s concentration gradient
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Active transport is mainly driven in 3 ways 1. Coupled transporters couple uphill transport of one solute to the downhill transport of another 2. ATP-driven pumps use hydrolysis of ATP to uphill transport 3. Light driven pumps couple transport to light absorbtion
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Lecture5 - 01.21.11 Lecture 5: Membrane transport Ion...

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