Altitude physiology (BB)

Altitude physiology (BB) - MOV 365 Clinical Exercise...

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Hypobaric Environments: Implications for Exercise MOV 365 – Clinical Exercise Physiology
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Lecture Objectives Identify the effects of altitude on physiological responses to exercise Highlight limitations to sport and exercise performance at altitude Consider appropriate acclimatisation strategies Is altitude training effective in improving sea-level performance?
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Interest in altitude physiology Why…? § 1968 Mexico Summer Olympics; Winter Olympics § 50% steeplechase and 5000 m + medals – native “highlanders” § Popularity of mountaineering § Holidays – winter sports?
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Oxyhaemoglobin Dissociation Curve Veins at rest Arteries
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Oxygen transport – sea level vs. altitude
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Effects of Altitude Barometric pressure and PO2 alveolar and arterial PO2; haemoglobin (Hb) saturation e.g. Mexico City 2300 m, Andes 5500 m, Everest 8848 m Sea level 2000m 5500m 8848m PO2 (mm Hg) 159 125 80 42 Hb sat (%) 98 90 73 50
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Acute Physiological Responses (> 2000 m) Hyperventilation hypoxic drive (chemoreceptors/medulla) d cardiovascular response d plasma catecholamines
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Acute Physiological Responses (> 2000 m) Blood volume hypovolemia Metabolic d BMR (SNS activity) Cardiac output
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Acute Physiological Responses depletion and premature fatigue inadequate CHO and fluid intake (Pedersen & Steensberg, 2002, MSSE, 43(12): 2004) d leukocytes and IL-6
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Effects of Altitude on VO2max small ° from 600 m then >70% “ at 8,800 m Mexico City – air 24% less dense Cycle TT’s @ moderate altitude
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Expeditions to Everest
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Task performance Factors – hypoxia, task (sensory/motor), complexity, familiarity
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