Altitude physiology (BB) (full)

Altitude physiology (BB) (full) - MOV 365 Clinical Exercise...

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Hypobaric Environments: Implications for Exercise MOV 365 – Clinical Exercise Physiology
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Lecture Objectives Identify the effects of altitude on physiological responses to exercise Highlight limitations to sport and exercise performance at altitude Consider appropriate acclimatisation strategies Is altitude training effective in improving sea-level performance?
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Interest in altitude physiology Why…? § 1968 Mexico Summer Olympics; Winter Olympics § 50% steeplechase and 5000 m + medals – native “highlanders” § Popularity of mountaineering § Holidays – winter sports?
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Oxyhaemoglobin Dissociation Curve Veins at rest Arteries
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Oxygen transport – sea level vs. altitude
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Effects of Altitude Barometric pressure and PO2 and decrease with altitude reduced alveolar and arterial PO2; reduced haemoglobin (Hb) saturation 50% Hb saturation = unconscious e.g. Mexico City 2300 m, Andes 5500 m, Everest 8848 m Sea level 2000m 5500m 8848m PO2 (mm Hg) 159 125 80 42 Hb sat (%) 98 90 73 50
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Acute Physiological Responses (> 2000 m) Hyperventilation hypoxic drive (chemoreceptors/medulla) Increase in alkalinity of body fluids (CO2 washout) d cardiovascular response d plasma catecholamines increased resting and submaximal heart rate and cardiac output These offset the reduction in PO2 (partial oxygen presssure.
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Acute Physiological Responses (> 2000 m) Reduction in circulating Blood volume hypovolemia fluid loss = respiration, urine, shift in intracellular 25% change in plasma volume
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Altitude physiology (BB) (full) - MOV 365 Clinical Exercise...

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