Biochem_Ch. 13 - Chapter 13 Membrane Channels and Pumps...

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Chapter 13 Membrane Channels and Pumps Matching Questions Use the following to answer questions 1-10: Choose the correct answer from the list below. Not all of the answers will be used. a) aspartic acid b) gap junctions c) digitalis d) action potential e) cotransporters f) ABC proteins g) lipophilic h) acetylcholine i) ATPases j) connexin k) patch-clamp l) antiporter 1 ____________ These membrane proteins transport two species in opposite directions across the membrane. Ans: l Section: Introduction 2 ____________ This type of molecule can diffuse across a membrane without the aid of a transporter protein. Ans: g Section: 13.1 3 ____________ P-type ATPases transfer a phosphor group to this amino acid residue side chain. Ans: a Section: 13.2 4 ____________ A plant extract of steroids used to treat heart failure. Ans: c Section: 13.2 5 ____________ This family of transport proteins possesses a separate domain or cassette that specifically binds ATP. Ans: f Section: 13.3
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Chapter 13 Membrane Channels and Pumps 6 ____________ These membrane transporters couple the transport of one species to the downhill flow of another ion species. Ans: e Section: 13.3 7 ____________ This is a technique used to measure conductance across a membrane. Ans: k Section: 13.4 8 ____________ This is another name for a nerve impulse. Ans: d Section: 13.4 9 ____________ These are passages that exist between adjacent cells that allow passage of ions and small molecules. Ans: b Section: 13.5 10 ____________ Cell-to-cell junctions are composed of 12 molecules of this protein. Ans: j Section: 13.5 Fill in the Blank Questions 11 The specific transport of a species down its concentration gradient is referred to as _______________________. Ans: passive transport, or facilitated diffusion Section: Introduction, 13.1 12 Membrane pumps are energy ____________________. Ans: transducers Section: Introduction 13 In _________________ a phosphoryl group is transferred from ATP to a specific aspartate residue. Ans: P-type ATPases Section: 13.2 14 Cardiac steroids such as digitoxigenin inhibit the _______________________. Ans: Na + -K + ATPase pump Section: 13.2 15 A P-glycoprotein transporter is also referred to as MDR protein which is an acronym for _________________________. Ans: Multidrug-resistance Section: 13.2 2
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Chapter 13 Membrane Channels and Pumps 16 The lactose permease transports lactose into the cell along with a ______________. 17 The interconversion between two conformations of a transporter is sometimes referred to as __________________. 18 Tetrodotoxin, isolated from puffer fish, binds tightly and specifically to ___________ channels in nerve cells. 19 The acetylcholine receptor is an example of a ____________-gated channel. 20 ___________________ are an important class of channels that increase the rate at which water flows through membranes. Multiple Choice Questions 21 A channel that opens in response to binding a particular molecule is called a ________ channel. 22 Channels that open in response to membrane depolarization are called __________ channels. A) voltage-gated D) All of the above. B) symport E) None of the above. C) ligand-gated 23 When a molecule moves from a concentration of 10 - 4 M to 10 - 2
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