Biochem_Ch. 16 - Chapter 16 Glycolysis and Gluconeogenesis...

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Chapter 16 Glycolysis and Gluconeogenesis Matching Questions Use the following to answer questions 1-10: Choose the correct answer from the list below. Not all of the answers will be used. a) obligate anaerobes b) AMP c) Embden Meyerhof pathway d) NAD + e) gluconeogenesis f) UDP-glucose g) GLUT5 h) facultative anaerobes i) ATP j) magnesium k) galactosemia l) biotin 1 ____________ This is the process by which noncarbohydrate precursor molecules are converted into glucose. Ans: e Section: Introduction 2 ____________ This is another name for glycolysis. Ans: c Section: Introduction 3 ____________ These organisms cannot survive in the presence of oxygen. Ans: a Section: 16.1 4 ____________ This substance must be regenerated for glycolysis to proceed. Ans: d Section: 16.1 5 ____________ This intermediate is necessary for the conversion of galactose to glucose. Ans: f Section: 16.1 6 ____________ This molecule is an allosteric inhibitor of phosphofructokinase. Ans: i
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Chapter 16 Glycolysis and Gluconeogenesis Section: 16.1 7 ____________ This transporter is responsible for fructose uptake in the intestine. Ans: g Section: 16.2 8 ____________ This condition is a result of a genetic deficiency of a single “transferase” enzyme. Ans: k Section: 16.1 9 ____________ This essential nutrient is required for the carboxylation of pyruvate in humans. Ans: l Section: 16.3 10 ____________ This is an allosteric activator of glycolysis. Ans: b Section: 16.1 Fill in the Blank Questions 11 Glycolysis produces a net of ________ moles of ATP per one mole of glucose. Ans: 2, two Section: 16.1 12 Pancreatic ______________ is the digestive enzyme primarily responsible for the hydrolysis of dietary plant starch. Ans: α-amylase Section: Introduction 13 The key enzyme that regulates the pace of glycolysis is ____________________. Ans: phosphofructokinase Section: 16.1 14 The catalytic mechanism of the isomerization of a ketose into an aldose proceeds through an _________________ intermediate. Ans: enediol Section:16.1 15 The common structural domain of NAD + binding dehydrogenases is often called a ___________________ after the scientist who first recognized it. Ans: Rossmann fold Section: 16.1 16 In alcoholic fermentation, the decarboxylation of pyruvate requires a coenzyme that contains the vitamin ______________. Ans: thiamine or B 1 Section: 16.1 2
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Chapter 16 Glycolysis and Gluconeogenesis 17 A potent allosteric activator of liver phosphofructokinase is _____________________, which is produced from fructose-6-phosphate by PFK2. Ans: fructose-2,6-bisphosphate Section:16.2 18 In the absence of oxygen, _____________________ increases the expression of most glycolytic enzymes and the glucose transporters GLUT1 and GLUT3. Ans: HIF-1, or hypoxia-inducible transcription factor Section: 16.2 19 The ________________ cycle refers to the metabolic reactions by which glucose is converted into lactate in skeletal muscle, and then lactate converted back into glucose in the liver. Ans: Cori Section: 16.4 20 The first step in gluconeogenesis is the ___________________ of pyruvate to form oxaloacetate. Ans: carboxylation Section:16.3 Multiple Choice Questions 21 Which of the following are reasons that glucose is a common metabolic fuel used by living organisms?
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