dysrhythmiadrugsfall10

dysrhythmiadrugsfall10 - AntiarrhythmicAgents SusanHampson

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Antiarrhythmic Agents Susan Hampson
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What Is An Arrhythmia? Abnormality of electrical conduction in  the heart Also called dysrhythmia Heart beats in an unexpected manner Can be lethal!
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The Conducting System of the  Heart
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Types of Cardiac Arrhythmias Tachycardia (faster-than-normal HR) Bradycardia (slower-than-normal HR) Premature atrial contractions (PACs) or  premature ventricular contractions  (PVCs) Atrial flutter Atrial fibrillation or ventricular fibrillation Alterations in conduction
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Causes of Cardiac Arrhythmias Electrolyte disturbances that alter the  action potential Decreases in O2 delivered to the cells Structural damage changing the  conduction pathway through the heart Acidosis or accumulation of waste  products altering the action potential Drugs that alter the action potential or  cardiac conduction
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Classes of Antiarrhythmic  Drugs Class I  IA: Slow conduction, prolong repolarization IB: Slow conduction, shorten repolarization IC: Prolong conduction,no effect on  repolarization Class II Beta Blockers: Block beta receptors
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Classes of Antiarrhythmic  Drugs Class III Drugs that prolong repolarization Class IV Calcium Channel Blockers Block calcium influx Slow conduction Decrease myocardial contractility Increase refraction in AV node
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Class I A   Antiarrhythmics: Quinidine Therapeutic Effects/Uses Treat atrial and ventricular arrhythmias Maintain sinus rhythm Mode of Action Depresses myocardial excitability,  contractility Slows electrical conduction
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dysrhythmiadrugsfall10 - AntiarrhythmicAgents SusanHampson

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