N212painrevisedspring10 (1)

N212painrevisedspring10 (1) - TreatingPain,Inflammation...

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Treating Pain, Inflammation  ,Fever, Headache Susan Hampson
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    Treating Severe Pain Narcotic (Opioid) Analgesics VERY effective for pain management Level of pain dictates the drug and route 
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    Narcotic (Opioid) Analgesics Affect mu, kappa, and delta receptors Result is alteration in perception of pain,  general CNS depression Use of pharmacologic agents is ONE part  of pain management
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    Prototype: Morphine Therapeutic Effects/Uses Treat acute or chronic pain; treat moderate and severe  pain Pharmacokinetics Multiple routes Quick, sustained release form Pharmacodynamics Binds with opiate receptors in CNS; result is diminished  transmission of pain impulses 
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    Morphine Adverse Effects CNS depression Cardiac depression GI distress GU issues Overdose – life threatening
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    Morphine  Nursing Considerations Thorough pain assessment Use standard rating scale Treat pain at lower level ATC dosing Use other interventions Evaluate for relief!
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    Morphine  Patient Teaching Explain plan Teach use of rating tool, PCA Correct misconceptions Avoid driving, hazardous activities Keep away from children!
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    There Are Differences!! Tolerance Decreasing response to drug with use Physical Dependence Changes occur in cells; body needs drug for  steady state Addiction  Compulsive use and craving of drug
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    Hydromorphine (Dilaudid) Effects almost identical to morphine MORE potent than morphine; 1.5 mg = 10  mg morphine Oral, parenteral, rectal routes
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    Oxycodone  Oral formulation only Effects very similar to morphine High risk for abuse as street drug There are combination forms of drug with  aspirin, acetaminophen
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    Meperidine (Demerol) Similar analgesic effects to morphine Less potent; 75 mg meperidine = 10 mg  morphine Metabolism of drug yields chemical that is  toxic to CNS
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N212painrevisedspring10 (1) - TreatingPain,Inflammation...

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