Chapter8Sp10SC

Chapter8Sp10SC - Organic Chemistry 5th Edition Paula...

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Chapter 8 Substitution Reactions of Alkyl Halides Organic Chemistry 5 th Edition Paula Yurkanis Bruice
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The S N 2 Reaction Summarize what occurs in your own words: Two key terms: Nucleophile and leaving group. What is a nucleophile? Identify the nucleophiles in the above reactions. What is a leaving group? Identify the leaving groups. OH + CH 3 Br CH 3 OH + Br CH 3 C C + CH 3 CH 2 I CH 3 C CCH 2 CH 3 + I NH 3 + CH 3 Br CH 3 NH 3 + Br Sections 8.1 and 8.2
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The S N 2 Mechanism C H H H OH Key terms/concepts: Backside attack Pentacoordinate carbon Inversion Rate Law Section 8.2
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Structure of the Alkyl Halide Explain this trend based upon the S N 2 mechanism. Section 8.2
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Alkyl Bromides methyl ethyl isopropyl t -butyl
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Identity of the Leaving Group • Relative reactivities of alkyl halides • Why is this true? Section 8.3
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Nucleophiles Nucleophilicity is like basicity in many respects. What do a nucleophile and a base have in common?
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Chapter8Sp10SC - Organic Chemistry 5th Edition Paula...

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