chp 4 - Chapter 4 Integumentary Click to edit Master...

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Click to edit Master subtitle style Chapter 4 Integumentary System
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Fig 4.1
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Integumentary system ¢ Skin (largest organ) l Epidermis – epithelial tissue (keritanized) l Dermis – Conn. tissue ¢ Subcutaneous layers ¢ Accessory structures l Hair, nails, glands ¢ Muscles, nerves, blood vessels
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Primary Functions ¢ Protection ¢ Receive sensory information ¢ Temp. regulation ¢ Vitamin D synthesis
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Thin and thick skin ¢ Thick skin (4-6 mm) l Soles, palms, fingertips (protects against abrasion) l 5 epidermal layers ¢ Thin skin (0.5 – 1.5 mm) l All other skin l 4 epidermal layers
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Epidermis ¢ 4 cell types ¢ Keratinocytes (90%) l produce keratin ¢ Melanocytes (8%) l Produce pigment melanin ¢ Langerhans cells (>1%) l Aid in immune response ¢ Merkel cells (<1%) l Aid in tactile reception
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Epidermis – cont. ¢ Stratified squamous ¢ No blood vessels ¢ Cells migrate from deep layers to superficial ones (6-8 wks.)
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Stratum basale ¢ Single layer – cuboidal ¢ All 4 cell types ¢ Many are stem cells- constant mitosis l Rate changes as needed ¢ Attached to basement membrane Fig. 4.3
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chp 4 - Chapter 4 Integumentary Click to edit Master...

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