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centraldogma 371 - #$&01&2#3-45&6$%4...

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!"#$%" '()*+,-.#/ 01)) 2"#3-45 6$/%4 2"#3-45 6$/%4 7-" 893.:.3; !"#$% '()*(" "#$ %&' ()**+",-+' ."#/+$ /) 0#). &1 " ()23*+/+ ,+#+/&( '4'/+2 ()-*$ 5+ 36)$-(+$ -'&#, (%+2&("*' "#$ " ()23-/+6 ,+#+6"/+$ 789 '+:-+#(+; <# =>?>@ "# "6/&(*+ ."' 3-5*&'%+$ $+'(6&5&#, /%+ 1&6'/ '+*1A6+3*&("/&#, '4#/%+/&( 5"(/+6&" B +, -./0$1(2 3!'45 2.)6,78 /%"/ %"' " ()23-/+6 '+:-+#(+ "' &/' 3"6+#/; C) D+6&14 /%"/ /%+4 %"$ '4#/%+'&E+$ " #+. )6,"#&'[email protected] F+#/+6G' /+"2 3-/ 789 '+:-+#(+' &# +, -./0$1(2 3!'452.)6,7 /%"/ '3+** )-/ '+(6+/ 2+''",+'; C%+ '"2+ 789 '+:-+#(+ &' 36&#/+$ )-/ H /&2+' BI-'/ 56)0+# &#/) $&11+6+#/ /6&3*+/ 6+"$&#, 16"2+'J; K'+ /%+ +<=!>? >[email protected]@?A 8B<=C 82<6 '+:-+#(+ "556+D&"/&)#' B%&#/@ %&#/J &# /%+ ()$)# /"5*+ /) -#()D+6 /%+ '+(6+/ 2+''",+ %&$$+# &# "# )3+# 6+"$&#, 16"2+ BLMNJ ; C%+ LMN' &# /%&' '4#/%+/&( 5"(/+6&" '/"6/ .&/% /%+ ()$)# OG 9CP HG B.%&(% &' .6&//+# "' OG 9KP HG &# /%+ ()$)# /"5*[email protected] 5+("-'+ 2M89 &' /6"#'*"/+$ &#/) "2&#) "(&$'J; C%+ 789 '+:-+#(+ 5+*). $)+' #)/ +#()$+ "#4 &#/6)#'; Watson #1 5’- AAA TTT ATC GTT CTG TGT TCT CTA CTC CAA TTG CAC GAC ACA TTG AA -3’ 3’- TTT AAA TAG CAA GAC ACA AGA GAT GAG GTT AAC GTG CTG TGT AAC TT -5’ #4 Crick Watson #2 5’- A AAT TTA TCG TTC TGT GTT CTC TAC TCC AAT TGC ACG ACA CAT TGA A -3’ 3’- T TTA AAT AGC AAG ACA CAA GAG ATG AGG TTA ACG TGC TGT GTA ACT T -5’ #5 stop R E T N E V G I A R C met Crick (please note that on an exam you should include methionine in your answer if we ask you to write out the amino acid sequence) Watson #3 5’- AA ATT TAT CGT TCT GTG TTC TCT ACT CCA ATT GCA CGA CAC ATT GAA -3’ 3’- TT TAA ATA GCA AGA CAC AAG AGA TGA GGT TAA CGT GCT GTG TAA CTT -5’ #6 Crick "# $%&' () '%* )*+,*' -*))&.*/ 0() 1&-*2 3,&(. 4*1'*, 5# 61 7%(+% 89: )',&1; <$&')=1 >"? $&')=1? >5?
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