nucleic acids spring 2011 - Nmfiag<31...

Unformatted text preview: Nmfiag } <31 Wgcrfi“ @Ldebfly Whose»th 0:51:53: 1 W31 xbo'nuflaz‘c DNA '3 Semfic Mae/0‘09 L3 ewes) (LUV) RM 3 vaxoh‘mns {m anumw o9w0~3g in mafia?) probing “\QOWRW (1' WA} é $¥mm3 PmNGQWQ ,SWU& ‘ 3133M wbogowQ/ '. ' ‘ mgpsenaaf§20JPr CmQNAyS; Garfies Wméia £61” WW1? _ \thx 31% Us.me nucLeE c acids, 2 DNA —>,~ mRWJc épmfin . D»3R&F¢s§e&$m M “*1? (SWSgWEE , ' ‘ ‘ Mondmrs 0Q dekzic ZWLLEOW'DE—Sfig” math . , Wei: ‘ h.’rroQ:-HW:S ‘ ' @erxkoséwdgmv - ' AZ W O“? demujwbosefin DNA) 1/ng ' I f [46% W wudev; \ \g/JA Mirm& ’ro cafbm X“ "/é 5'01,me w‘ ' Mm, guflm" ski/)0“, @ W'hggemmg b036, (Ouabyyfls . w bamréhefi‘, +o“mr\om=éfl %sq3w_ ‘ , , hike enms bases are; in 1ths: v in) ~ ‘ ‘ « fin c s: w nmmmg b memw a“ '52?“ CF)"DN$F®A\;‘ W W b m ‘ fhogenws bases 8) (iii-[55 , W59“ ATT {SM/Wag EDNA: Sifimmfig {Paww} " WEEK 55ch mam KM, “\cevwci 4m a“ mmaw m w W Sufism" mphmwkmlfi, chm W W m U» W“ Rh}; «Vb We; \MMLW ““ “W Mbefimfiwmwmwcfi NNQWWM wmswg Wad}? Wm SWWEflVW «23%: “3:19. W“ m. ‘- ma W WW ‘5me » @531va WWE W» yam R%Q$V;W -« firm m» Wm a? (wwak W “E gamfia V W “3%de E36115} QM ghaggémfe m awbmggflm gait—3M“ *3 JIM, '29ng 3M4 m. M mflfi gww Wk mrbmfifwgpfiw Qmfiar (I fiumgg fii vv-W ‘ (3 b u Q WW "hm gufimww?w$?% ~ mam/w "Wm @??i§${§ffi iv 45% a»? M‘mag" w W wagmwi gm W 93W 554? (:ka flair b MM a m \ ~ ‘ a; g" ““' QM 3 awkfia W J“ megimmmér W‘ 5/ 3—ymcfl. {a 3i EV $§5WELF~ 5’ 51,“. Whawwmuwwwfimmm @N‘E ‘fJR-Mi’ib 6% DN A magnesia W iiiflflfifififl behueen Aamd”T* ' H ‘ I ‘ hmdeofi‘cig i Thyminé (T) - /N W , 0 sg‘gar 9. ‘i ADENINE (A) THYMINE (T) E H .. MWQ’I} _, V v . ‘ . . .. ~. t EM [,0 H .\. /N / V . . . . “k Sugarg Nw< 53..“ ..... .0 / GUANINE (G) v Gunning) (G) DNA nucleotide ‘ >6H ‘ H ‘ Sugar (deoicyribqse) ’ » <-—~—~——" i" I ‘ . double ‘ J » j ,‘momoflkflo£‘DMA \ #600,533 {ml/x ' 3.4 nm ‘ S Purine + purine: mo wide Pyrimidine + pyrimidine: too narrow Purine + pyrimidine: width consistent with X-ray data ...
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