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History of Fluid Mosaic Model For more on this history, see: http://www1.umn.edu/ships/9-2/membrane.htm
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Phospholipids—Lipid Bilayar
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Membrane Fluidity Note that proteins can also be anchored to cytoskeleton Lipid bilayers are fluid, at normal body (organismal) temperatures, but typically only in two dimensions!
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Membrane Proteins
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Membrane Protein Functions
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Membrane Assymetry This asymmetry allows the cell to automatically differ its intracellular environment from that existing extracellularly
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Membrane Glycoproteins
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Fluid Mosaic Model
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Movement Across Membranes Passive Transport Simple diffusion (passive diffusion) Facilitated diffusion Transporters Uniporters Cotransporters Channel proteins Active Transport Pumps Group Translocation Electrochemical Gradients
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Movement Across Membranes Passive Transport Simple diffusion (passive diffusion) Facilitated diffusion Transporters Uniporters Cotransporters Channel proteins Active Transport Pumps Group Translocation Electrochemical Gradients
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Primer on Diffusion Diffusion is movement from area of high concentration to low Diffusion is Passive Transport: no energy is required
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Simple Diffusion Across Bilayers Passive diffusion - unaided by transport proteins - no metabolic energy expended - movement is down chemical concentration gradient - diffusion rate is proportional to concentration gradient and hydrophobicity - rate limiting step is movement across hydrophobic portion of membrane - the greater the hydrophobicity of a water-soluble molecule, the faster it diffuses across phospholipid bilayer.
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Simple Diffusion Across Bilayers
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Diffusion Across Membranes
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Osmosis: H 2 0 Down Conc. Gradient
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Osmosis: H 2 0 Down Conc. Gradient Equilibrium
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Tonicity: H 2 0 Down Conc. Gradient
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This note was uploaded on 06/03/2011 for the course BIO 113 taught by Professor Swenson during the Spring '08 term at Ohio State.

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campbl08 - For more on this history, see:

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