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campbl19 - Metazoan Phenotypic Complexity Less...

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Metazoan Phenotypic Complexity
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Chromatin Packing Less Transcription Less Methylation
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Histones (Nucleosomes)
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Loops of 30 nm Chromatin
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Eu- vs. Hetero-Chromatin Euchromatin Hetero- chromatin
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Phenotypic “Plasticity” To survive, organisms must be able to adapt to changes in their environments These adaptations can occur at many different levels: 1. Organisms can change their behaviors (ch. 51) 2. Organisms can modify the expression of their proteins post-translationally (ch. 6 & 11) 3. Organisms can change what genes are expressed (ch. 11, 18, & 19) 4. Organisms can display norms of reaction during development and/or can acclimitize (ch. 14, 21, 44) 5. Culture (learned behavior) can be modified (ch. 34) 6. Populations can genetically evolve (ch. 22 & 23)
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Control of Eukaryote Gene Expression
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Signal Transduction Pathways
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Control of Eukaryote Gene Expression
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Genomic Imprinting
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Control of Eukaryote Gene Expression
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Positive Control (in prokayotes) Protein-DNA binding Enhances Transcription
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Transcription Factors
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Enhancer Sequence
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DNA Binding Proteins
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Control of Eukaryote Gene Expression
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