Lecture 18

Lecture 18 - Lecture 18 Chromosomes Mandalian Genetics =...

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Lecture 18 Chromosomes Mandalian Genetics = chromosomes: Chromosomes are related to inheritance More or less does not make a difference, we need all our chromosomes Ascaris Egg Looked at germ line (cells that produce next individual) Scientist noticed that: (1) Divide in precise way If they have cells the next embryo will produce it in the exact same way (2) Somatic cells lose pieces of chromosomes Method of seeing if chromosomes are important or not The cells in the germ line were never losing chromosomes Cells important for creating new individual Conclusion : You need the whole set of chromosomes Metaphase Chromosome Metaphase Chromosomes 1 | P a g e
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In non dividing cells individual chromosomes are not visible During mitosis and meiosis chromosomes condense and become visible Condensation of metaphase results from folding of several 30nm chromatin fibres Each metaphase chromosome is made up of two sister chromatids Centromere : Links the sister chromatids in the center Recruits specific proteins that form the kinetochores which in turn recruits the spindles 2 | P a g e
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Chromatin Folding Model for Chromatin Folding Interphase nucleus: Material of black and white intensities Some areas of nucleus are much less dense than others, these are chromosomes that are partially decondensed Two main structures:
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Lecture 18 - Lecture 18 Chromosomes Mandalian Genetics =...

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