ATPsynthase - 1 ATP Cycle Ion Translocating ATPases P-type...

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Unformatted text preview: 1 ATP Cycle Ion Translocating ATPases P-type ATPases V-type ATPase F-type ATPase F 1 F ATP Synthase 2 Cellular Locations of the F 1 F ATP Synthase Family Energy Transduction and F 1 F ATP Synthase 3 Peter Mitchell and the Chemiosmotic Hypothesis The discharge of the electrochmical gradient of protons is coupled to the phosphorylation of ADP making ATP. Proton Motive Force D p = Dm Dm H = Dy Dy + + 2.3 RT D pH/F = 0.224 V Electrochemical Membrane pH gradient H + gradient Potential R: gas constant T: absolute temperature F: energy change of mole H + in a 1 Volt field D p = 5.2 kcal/mole but D G ’ = 7.2 kcal/mol for ATP Electronmicrograph of the E. coli F 1 F ATP Synthase Wilkens. 2000. J Bioenerg. Biomemb . 32, 333-339 4 Structural Analysis of F 1 F ATP Synthase Stock et al. 1999. Science 286, 1700-1705 F 1 F lipid bilayer cytoplasm extracellular Escherichia coli F 1 F ATP Synthase Pedersen et al . (2000) J. Bioenerg. Biomemb . 32, 325-331 Peripheral Stalk Rotary Stalk a 3 b 3 gde gde ab 2 c 9-12 5...
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This note was uploaded on 06/07/2011 for the course BCH 6206 taught by Professor Staff during the Spring '08 term at University of Florida.

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ATPsynthase - 1 ATP Cycle Ion Translocating ATPases P-type...

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