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Unformatted text preview: q 1,
1, 2 3, 4 i, j m, n What are the possible distributions of alleles in the two sisters (IJ and MN), and what fraction of
them produce 0, 1, and 2 genes that are identical by descent?
Sister IJ Sister MN, 13
14
23
24 13
14
23
24 Make a table; rows and columns are possible genotypes of sisters IJ and MN; cells are # of
alleles identical by descent 13 Sister NM
14
23 24 2
1
1
0 1
2
0
1 0
1
1
2 Sister IJ
13
14
23
24 1
0
2
1 The expected NUMBER of alleles I by D is: (4/16)(2) + (4/16)(0) + (8/16)(1) = 1
The expected PROPORTION of alleles I by D is 1/2, so rFS = 1/2 ...
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 Fall '08
 BAER
 Genetics, #

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