Pharm 1000 test 2 material

Pharm 1000 test 2 material - Pharm 1000 test 2 material...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Pharm 1000 test 2 material 28/09/2010 12:28:00 9/28/10 Pharm 1000 Opioid (Narcotic) analgesics Drugs Prevent or Relieve Pain: General anesthetics either, cholorform Throughout the body Local anesthetics novacaine Specific area Analgesics NSAIDS Opioids (narcotics) o Tylenol/vicoden Pain and Endogenous Opioids Good to tell you when something hurts Bad when it hurts Pain receptors Sensory pain nerve fibers spinal cord glutamate and substance P release Thalamus and cerebral cortex might be different Endongenous opioid peptides Vertebrates endorphins (tells you that you are being overstimulated) Acupuncture relieves certain kind of pain OPIUM History Thousands of year o Diarrheaalso good for pain Opium War o French and Chinese Chinese people started being addicted to Opium. o Hong kong British island French connection huge drug bust movie Current sources of Heroin SW Asian 95% Afghanistan Source and composition of opium Poppy, Papaver somniferum actual name 175-250 hrs 1kg = 2.2lb opium = 100 g of morphine or heroine Opium alkaloids Morphine 10% o Die from this from respirator depression Codeine - 5% Morphine activates mu and kappa..some only activate kappa receptor Europhia Mu receptor feeling of greatness Dysphoria kappa receptor shitty Pupil constriction - MU Physical dependence do not produce dependence Opiods Pure agonistis use for severe pain Mu agonists Mixed agonists moderate pain kappa agonists Pure antagonsists antitodes for morphine poisoning Morphine Pharmacological actions & therapeutic uses Analgesia Subjective awareness of pain not elevation pain threshold Mu opiod recptors: spinal cord + brain MOST EFFECTIVE FOR REAL PAIN Moderate-severe pain you should only use vicodin with serious pain or youre fucked o Pain-relieving strategies Prevent pain Analgesic ladder start with Tylenol Patient-controlled analgesia ring a bell and nurse gives it to you or use an IV when pain comes Cough antitussive (codeine) use for hacking cough that you get from smoking or when you have something caught expectorant used when you have a phlegm Miosis pinpoint pupils if you go from sun to movies = they dialate Morephine users have small pupils GI Tract Constipation o Antidiarrheal Paregoric camphorated opium tincture Loeramide Acute toxicity Heroin legal in UK used for pain...
View Full Document

This note was uploaded on 06/05/2011 for the course COMM 1100 taught by Professor Na during the Spring '10 term at UConn.

Page1 / 38

Pharm 1000 test 2 material - Pharm 1000 test 2 material...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online