Z54_HIOTE_Saier_2009_5-2-2011z

Z54_HIOTE_Saier_2009_5-2-2011z - Next-generation genomics...

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Next-generation genomics technology, Next-generation genomics technology, Conservation and Extinction Conservation and Extinction Oliver A. Ryder San Diego Zoo’s Institute for Conservation Research www.zooconservation.org
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Genome 10K Genome 10K http://genome10k.soe.ucsc.edu/ Frozen Zoo – living somatic cells collection 7,500 individuals 131 families 700 taxa 7,100 mammals 88 families 580 taxa 100 reptiles 30 taxa 270 birds 100 taxa 1 amphibian 1 taxon 1 fish 1 taxon
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New Scientist 23 January, 2009 New Scientist 23 January, 2009 Sabre-toothed tiger ( Smilodon fatalis ) Extinct: ~10,000 years ago DNA preservation: 3/5 Suitable surrogate: 3/5 Neanderthal ( Homo neanderthalensis ) Extinct: ~25,000 years ago DNA preservation: 1/5 Suitable surrogate: 5/5 Short-faced bear (Arctodus simus) Extinct: ~11,000 years ago DNA preservation: 3/5 Suitable surrogate: 2/5 Tasmanian tiger ( Thylacinus cynocephalus ) Extinct: 1936 DNA preservation: 4/5 Suitable surrogate: 1/5 Glyptodon ( Doedicurus clavicaudatus ) Extinct: ~11,000 years ago DNA preservation: 2/5 Suitable surrogate: 1/5 Woolly rhinoceros ( Coelodonta antiquitatis ) Extinct: ~10,000 years ago DNA preservation: 4/5 Suitable surrogate: 5/5 Dodo ( Raphus cucullatus ) Extinct: ~AD 1690 DNA preservation: 1/5 Suitable surrogate: 3/5 Giant ground sloth ( Megatherium americanum ) Extinct: ~8000 years ago DNA preservation: 2/5 Suitable surrogate: 1/5 Moa ( Dinornis robustus ) DNA preservation: 3/5 Suitable surrogate: 2/5 Irish Elk ( Megaloceros giganteus ) Extinct: ~7700 years ago DNA preservation: 3/5 Suitable surrogate: 2/5 Giant beaver ( Castoroides ohioensis ) Extinct: ~10,000 years ago DNA preservation: 2/5 Suitable surrogate: 1/5 Gorilla ( Gorilla gorilla ) Extinct: Almost DNA preservation: 5/5 Suitable surrogate: 5/5
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Conservation Genomics Potential applications of genome sequencing studies that contribute
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