Ch42_Lecture-Spr11

Ch42_Lecture-Spr11 - Immunology: Gene Expression and...

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Unformatted text preview: Immunology: Gene Expression and Natural Defense Systems http://microbiology.otago.ac.nz/dept/staff/buchan_glenn/images/Macrophage.jpg 42 18 Immunology: Gene Expression and Natural Defense Systems 42.1 What Are the Major Defense Systems of Animals? 42.2 What Are the Characteristics of the Nonspecific Defenses? 42.3 How Does Specific Immunity Develop? 42.4 What Is the Humoral Immune Response? 42.5 What Is the Cellular Immune Response? 42.6 How Do Animals Make So Many Different Antibodies? 42.7 What Happens When the Immune System Malfunctions? www.nyscience.org/whataboutaids/whatis/immune/assets 42.1 What Are the Major Defense Systems of Animals? Animals have various means of defense against pathogens agents that cause disease Defense systems are based on recognition of self (ones own) and nonself (foreign) molecules www.nyscience.org/whataboutaids/whatis /immune/assets 42.1 What Are the Major Defense Systems of Animals? Three phases of defense response: Recognition phase organism must discriminate between self and nonself Activation phase r ecognition event leads to mobilization of cells and molecules to fight invader Effector phase m obilized cells and molecules destroy invader 42.1 What Are the Major Defense Systems of Animals? Two general types of defense mechanisms: Nonspecific defenses , or innate act rapidly include skin, phagocytic cells, and molecules toxic to invaders Specific defenses , or adaptive aimed at specific pathogens Include antibody production Slow to develop and long-lasting 42.1 What Are the Major Defense Systems of Animals? Mammals have both kinds of defense systems They work together as coordinated system Nonspecific defenses are first line of defense , and are tremendously important http://www.actagainstallergy.co.uk/aaa/_images/system_01.gif 42.1 What Are the Major Defense Systems of Animals? Parts of the immune system Lymphoid tissues include thymus , bone marrow , spleen , and lymph nodes essential parts of defense system Jump to Slide #45 Lymph node Figure 42.1 The Human Lymphatic System 42.1 What Are the Major Defense Systems of Animals? Blood plasma contains ions, small molecular solutes, soluble proteins Red blood cells stay in closed circulatory system White blood cells and platelets are also found in plasma http://www.med-ed.virginia.edu/courses/path/innes/images/nhjpeg/nh%20blood.jpeg 42.1 What Are the Major Defense Systems of Animals? Lymph fluid derived from blood and other tissues From tissues, lymph moves into lymph system vessels Lymph vessels join and eventually form thoracic duct , which joins circulatory system at a vein near heart 42.1 What Are the Major Defense Systems of Animals?...
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Ch42_Lecture-Spr11 - Immunology: Gene Expression and...

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