Test 3 SI Notes - SI Notes Chapter 12 10/01/2010 (Leslie)...

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Unformatted text preview: SI Notes Chapter 12 10/01/2010 (Leslie) Binary fission bacteria divide Somatic cells body cells o Diploid 2n=46 chromosomes o Mitosis Gametes sex cells o Haploid n=23 chromosomes o Miosis Cell cycle prepares cell for division o Interphase G1- Cell grows Restriction points decide where to continue cell cycle o Cell cycle S DNA replication G2- check for damage M phase mitosis/meiosis G0- cell will enter if damaged Cells may be destroyed or fixed MAD genes signal that the spindle is attached to centromere Kinetochore special region of centromere that the spindle will attach to Cell chemicals power cell cycle o Kinase enzymes are phosphorilated from ATP o Cyclin Normal cells divide 20-50 times o Have telomeres located on the end of chromosomes Non coded regions of chromosome Get shorter as you age Cell dies when it gets to the end o Telomerase Only enzyme that can replace it o Cancer cells dont obey Density dependant inhibition o When cells next to each other wont divide Ex. Maximum number of people in the room Anchorage dependency o Cell wont divide if not attached to where its supposed to be Chapter 12 10/04/2010 (Shane) Mitosis o Somatic cells Ex. Hair cell o Diploid 46 chromosomes in human cells o The new cell and the old cell are identical o Prophase Break down nuclear membrane Chromosomes coil and condense so theyre easier to move First time chromosomes are visible o Metaphase Chromosomes line up on metaphase plate In the middle of the cell Spindle fibers attach o Anaphase Chromosomes pulled apart o Telophase Reverse of prophase Cytokinesis When the cell actually separates Plant cells divide from the inside out and animal cells divide from the outside in Normal cells o Go through mitosis 20-50 times Because telomere, which controls cellular suicide, gets shorter with each division; When telomere reaches the bottom the cells dies o Density dependent inhibition When two cells meet they stop dividing o Anchorage dependency Cells have to be attached to something to divide o P53 Master Tumor Suppressor Cancer cells o Divide forever because they have telomerase, which keeps telomeres lengthened so they never reach the bottom o P53 If its turned on, the tumor is benign If its turned off, the tumor is malignant Chapter 13 10/11/2010 (Shane) n = number of homologues 2n = haploid; n = diploid For each chromosome, theyre two sister chromatids Centromere what holds the sister chromatids together 2n=72 o Number of chromosomes - 72 o Number of homologues - 36 o Number of sister chromatids - 144 o Number of centromeres 72 Meiosis o Prophase I Synapsis Chiasmata o Metaphase I Chromosomes line up two by two o Anaphase I Homologous chromosomes separate o Telophase II Four haploid Mitosis o Prophase I No synapsis or chiasmata o...
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This note was uploaded on 06/07/2011 for the course BSC 2010c taught by Professor Janewaterman,pamelathomas during the Spring '07 term at University of Central Florida.

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Test 3 SI Notes - SI Notes Chapter 12 10/01/2010 (Leslie)...

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