Chapter 16 The Molecular Basis of Inheritance

Chapter 16 The Molecular Basis of Inheritance - Chapter 16...

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Chapter 16 The Molecular Basis of Inheritance DNA is the genetic material Replication of DNA to pass genetic material in cell division Experimentation to explain mechanism of inheritance Morgan – determined that genes (units of inheritance) are located on chromosomes Chromosomes known to be composed of DNA and proteins Is the genetic information contained in the DNA or the proteins? Before 1940, proteins seemed to be heritable material Genetic experiments carried out with peas, fruit flys, humans Bacteria and viruses that infect them are good experimental models to distinguish roles of proteins and DNA Simple and small amount of DNA Design experiments to identify if the heritable material is DNA or the proteins Discovery of Frederick Griffith 1928 - Used bacteria Streptococcus pneumoniae 2 strains - one virulent or pathogenic and causes pneumonia in mammals (mice); the other strain is nonpathogenic
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