# answer-prob1e_sp11 - A nswers to Patient problem 1-e Worth...

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Answers to Patient problem 1-e Worth 50 points 1. [1 point] Freezing point depression means that the freezing point will drop by 1.86 degrees for each 1 osmole/kg. Set up ratio: 1 OsM/1.86 degrees = x OsM/0.558 degrees x = 0.3 OsM or 300 mOsM * *Assuming that physiological solutions are so dilute that osmolality = osmolarity. 2. [4 pts] deuterium oxide: 41.5 liters = total body water 0.3 osmoles/L x 41.5 L = 12.450 osmoles in total body inulin: 11.3 liters = extracellular volume 0.3 osmoles/L x 11.3 liters = 3.390 osmoles in ECF Evans blue: 2.73 liters = plasma volume (not relevant to rest of problem) 0.3 osmoles/L x 2.73 liters = 0.819 osmoles in plasma S/V = OsM. You know volumes for total body, ECF, and plasma, and you know osmolarity from Q1. Calculate solute amount for each compartment. This becomes initial values for Q3-9. O x V = S [1 point per compartment] Total body ECF Plasma* ICF Solute 12.450 osmol 3.390 osmol 0.819 osmol 9.06 osmol Volume 41.5 L 11.3 L 2.73 L 30.2 L Osmolarity 0.3 OsM 0.3 OsM 0.3 OsM 0.3 OsM * Plasma is part of the ECF and is included in the 11.3 L of the ECF. ICF = Total minus ECF. * Simplest way to get ICF values in most cases is to subtract.

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answer-prob1e_sp11 - A nswers to Patient problem 1-e Worth...

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