05 Control Mechanisms

05 Control Mechanisms - Control Mechanisms Control...

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Unformatted text preview: Control Mechanisms Control Mechanisms Text Reference: Chapter 5.5 Monday March 28, 2011 Gene Expression Gene Expression 42 000 genes code for proteins in humans Inefficient to transcribe ALL of them Eg: insulin is only transcribed when glucose is present some proteins are always needed we call these housekeeping proteins Transcription Factors turn on genes when needed Proteins bind to DNA and help RNA polymerase bind to transcribe Gene regulation On/off genes depending on organism requirements 4 Levels of Gene Expression 4 Levels of Gene Expression Type of Control Description 1. Transcriptional Regulates which genes are transcribed from DNA to mRNA Controls the rate at which transcription occurs 2. Posttranscriptional mRNA molecules undergo changes in the nucleus before translation occurs Introns are removed exons are spliced together 3. Translational How often and how quickly mRNA transcripts are turned into proteins. Controls the amount of time it takes for mRNA transcripts to be activated and for cytoplasmic enzymes to destroy it 4. Posttraslational Many proteins must pass through the cell membrane to function. The...
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This note was uploaded on 06/12/2011 for the course BIOL CHEM 1000 taught by Professor Williampietro during the Spring '10 term at York University.

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05 Control Mechanisms - Control Mechanisms Control...

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