GERD SP09 sue

GERD SP09 sue - Esophageal Disorders: GERD Gastroesophageal...

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Esophageal Disorders: GERD Gastroesophageal Reflux Disease Susan Hampson
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GERD Is really a syndrome Problem is backward flow of gastric contents into esophagus Can involve patient’s report of symptoms and/or actual cellular changes in esophagus
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GERD: Pathophysiology Defenses of lower esophagus overwhelmed Esophageal irritation and inflammation (esophagitis) occur Gastric and intestinal enzymes cause corrosive damage to mucosa (Pepsin, trypsin)
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GERD: Pathophysiology Predisposing Conditions Hiatal hernia Incompetent LES (Lower esophageal sphincter) Decreased esophageal clearance Impaired esophageal motility Decreased gastric emptying
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GERD: Incompetent LES Sphincter normally does NOT allow acidic stomach contents to flow backward into esophagus If sphincter is incompetent, result is Decreased pressure in lower esophagus Gastric contents are at higher pressure so will move to area of lower pressure Factors that decrease pressure at LES include ETOH, foods, medications, obesity, pregnancy, hiatal hernia, cigarette smoking
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This note was uploaded on 06/20/2011 for the course NURS 344 taught by Professor Hampson during the Spring '11 term at St. Xavier.

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GERD SP09 sue - Esophageal Disorders: GERD Gastroesophageal...

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