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Bio 260 Endocrine System

Bio 260 Endocrine System - SC Nerves Brain Nerves Sense...

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SC & Nerves Brain & Nerves Sense organs Endocrine system Cardiovascular system (blood, heart, vessels) Lymphatic system Exam 3: Tuesday 11-18-08
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Endocrine Glands Regulate other systems Homeostasis Different from NS Composition Glands Messenger Hormone How delivered Blood Target Many cells Time Slow; long-lasting
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Endocrine glands Hormones Chemical messengers Communication Effect cell metabolism Triggered by blood concentrations Feedback mechanisms Target cells Receptors can respond
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Only cells with receptors can respond Shape of receptor : lock-and-key
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Travel via bloodstream : local or distant Two types Peptide hormones Many glands produce Types Modified amino acids Peptides Proteins Glycoproteins Steroid hormones Modified cholesterol (lipids) Produced by ovaries & testes Hormones are chemical messengers Selective
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Peptide hormones require second messengers Types cAMP - c yclic a denosine m onophosphate cGMP - c yclic g uanosine m ono p hosphate IP 3 - i nositol tri p hosphate DAG - d i a cyl g lycerol Example of activity: Kin ase * Phosphorylation Conformational change Effect Channels open/close, vesicles released, enzymes*
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Binds to membrane receptor Second messenger* ATP cAMP AC = adenyl cyclase Kinase* Enzymes* Metabolism effected Glycogen Glucose Glucose Bloodstream Back to setpoint The action of peptide hormones AC
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