BIO_101_Lecture_Ch5-membranes,diffusion[1]

BIO_101_Lecture_Ch5-membranes,diffusion[1] - BIO 101...

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BIO 101 Chapter 5 QUIZ tonight, EXAM #1 next class, LAB started this week!
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Cystic Fibrosis CFTR is a protein channel which allow for the movement of Cl-, followed by water Thin, slippery film is produced on surface of cell/tissue Single amino acid change in protein causes the CFTR to be destroyed before reaching cell membrane No film causes mucus to dry out and become sticky
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Sickle Cell Anemia The difference in red blood cell shape is due to a single change in ONE amino acid in the chain that folds to form the hemoglobin molecule. This change in the protein (change in shape) causes inflammation as normal blood flow is disrupted. Cells can easily become deprived of oxygen.
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Organization of Cell Membrane Semi-permeable Lipid bilayer with embedded proteins Fluid mosaic model Side chains face outward # and kinds of proteins vary
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3 types of transportation possible across membrane…. Diffusion- substance move from area of high concentration to area of low concentration Facilitated Diffusion- diffusion that utilizes specific channel proteins in membrane Active Transport- substance move from area of low concentration to area of high concentration, requires energy
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Why is movement across a membrane important? Cells need raw materials: Glucose Amino acids – O 2 Cells need to get rid of waste: – CO 2 metabolic waste Cells need to maintain water balance: – Aquaporins allow passage of H 2 O across membrane Control volume Maintain proper pH
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2 Groups of Membrane Proteins Integral – most span across bilayer, interact with hydrophobic parts of bilayer (interior) and have hydrophilic sections on both surfaces Peripheral - located at one of the surfaces
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This note was uploaded on 06/21/2011 for the course BIO 101 taught by Professor Staff during the Spring '08 term at Northern Virginia Community College.

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BIO_101_Lecture_Ch5-membranes,diffusion[1] - BIO 101...

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