Microsoft PowerPoint - INTRODUCTION to structure of protein - part A

Microsoft PowerPoint - INTRODUCTION to structure of protein - part A

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Structural Classification of Proteins 2
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SCOP Database The recent exponential growth in the number of proteins whose structures have been determined by X-ray crystallography and NMR spectroscopy means that there is now a large and rapidly growing corpus of information available. Nearly all proteins have structural similarities with other proteins and, in many cases, share a common evolutionary origin . The knowledge of these relationships makes important contributions to molecular biology and to other related areas of science. 3
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The Homology Search . ١ Enter a sequence . ٢ Obtain a list of any structures to which it has significant levels of sequence similarity 4
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Proteins are clustered together into families on the basis of one of two criteria that imply their having a common evolutionary origin: roteins that have residue identities of 0 and proteins that have residue identities of 30% and greater proteins with lower sequence identities but whose
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Microsoft PowerPoint - INTRODUCTION to structure of protein - part A

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