{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Microsoft PowerPoint - INTRODUCTION TO Structure OF Protein - PART B [

Microsoft PowerPoint - INTRODUCTION TO Structure OF Protein - PART B [

Info icon This preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
INTRODUCTION TO Structure OF Protein PART B By S. M. S. M. S. M. Rafigh Rafigh Rafigh 2011
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Protein Structure Classification Determining the respective structural classes of new proteins by manual or the semi- automatic methods becomes inadequate nowadays. Classifying a new protein through traditional structural comparison. 2
Image of page 2
Structural Fingerprints Use data mining techniques to generate the structural fingerprints for the various structural classes. A fingerprint is a set of concise and representative features that are common to all the protein structures in a given class. 3
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Secondary Structure Element (SSE) In a protein, certain portions of its AA sequence folds into specific shapes such as helices (H) and sheets (E) due to the forces of nature such as hydrogen bonds and disulphide bonds . 4
Image of page 4
Topology The arrangement of SSEs within a protein is called its topology 5
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Classification Based on Fragments Secondary structure classes are too restrictive to describe protein structures. How many local structure categories are necessary and sufficient? Since the protein structures are complex, we try to break up the problem and seek for additional levels of structural organization.
Image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern