ch369_sp11_class_4_notes

ch369_sp11_class_4_notes - Regarding amino acids & proteins...

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Recognize all 20 a.a., know 3 letter abbreviations, and properties (hydrophobic, hydrophilic, charged). Be able to draw them individually, and linked together in a peptide chain. I won’t ask you to draw Trp, Ile, Arg, or Lys on the exam (but be able to recognize them & know their properties).
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Rosalind Franklin (Kings College) recorded x-ray diffraction patterns from DNA fibers. Watson and Crick constructed a model of DNA with features that made chemical sense and was consistent with Franklin’s x-ray diffraction data.
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sugar-phosphate backbones
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When DNA structure was discovered in 1953, it was immediately recognized that base-pairing enabled each DNA strand to serve as a template for replication. 5’ 3’ 5’ 3’
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Major and minor grooves in DNA.
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RNA can also form base pairs. A = U C = G 2 strands of base paired RNA:
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DNA RNA Base paired DNA and RNA helices are quite different in structure. Why are DNA and RNA helices so different in structure?
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DNA RNA Why are DNA and RNA helices so different in structure? -OH group in RNA H-bonds with oxygen on ribose of adjacent nucleotide. This H- bond influences the orientation of the ribose ring in RNA. -OH H-bond
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RNA can also form complex structures: A stem-loop in a viral RNA.
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pseudoknot ” structure within a messenger RNA. Du, Giedroc & Hoffman (1996)
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This note was uploaded on 06/20/2011 for the course CHEM 369 taught by Professor Hoffman during the Spring '11 term at University of Texas at Austin.

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ch369_sp11_class_4_notes - Regarding amino acids & proteins...

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