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ch369_sp11_lipids_2_notes

ch369_sp11_lipids_2_notes - Todays topic More lipids...

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Today’s topic - More lipids & membranes (Chapter 8) .
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Some things to know - Structures of the most common fatty acids (palmitate, stearate). General structure of TAGs. Recognize omega-3 & omega-6 Fas. cis & trans Fas, saturated & unsaturated FAs. How do saturation and chain length influence m.p. Recognize phospholipids, sphingolipids, cholesterol.
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Which of these molecules is cis- oleic acid?
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Which of these molecules is a glycosylated sphingolipid?
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Several vitamins are lipids.
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Vitamins. Definition - Vitamin = organic compound that is required in small amounts in diet. Vitamin A Vitamin D Vitamin E Vitamin K B1, B2, B3, B5, B6, B7, B9, B12 Lipid vitamins Water soluble vitamins: (we will meet the water soluble vitamins later in the course)
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Sources in diet - Many plants, also meat, especially liver. Vitamin A is fat soluble. You can get too much, or too little if absorption is a problem. Vitamin A - Retinol Retinol (vitamin A) Some uses of vitamin A : Vision (11-cis-retinol bound to rhodopsin detects light in our eyes). Regulating gene transcription (retinoic acid receptors on cell nuclei are part of a system for regulating transcription of a number of genes).
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It is essential, but roles are unclear. Suggestions include neural membrane component, antioxidant. Obtained in diet, deficiency is rare. Vitamin E - Collectively refers to 8 related tocopherols.
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Vitamin K is required for proper blood clotting. It is used in synthesizing gamma carboxyglutamate, a post-translationally modified amino acid in prothrombin. Sources are vegetables and fruits, deficiency is rare.
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