Epithelia - Epithelia 09/14 ~ 1:25 PM Epithelia Page 1...

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Epithelia - 09/14 ~ 9/27/2010 September 21, 2010 1:25 PM Epithelia Page 1
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Cellularity 1. Not all tissues are cellular (some are dominated by self-product) <- i.e. bone) - Epithelia are very cellular - Polarity 2. Different appearance, function, and proteins attached Epithelia has 2 different ends because they are on the junction - Apical: facing lumen / top - Lateral: between epithelial cells - Basal: epithelia connected to rest of body - Specialized intercellular contacts (different junction organization) 3. Skin keeps moisture intact and protection --> strong junction for resistance Epithelia that aligns air sac of the lung for permeable gas i.e. skin vs. lung - - Attachment to BM + CT 4. BM is cellular (made up of cell product) - Avascular but innervated 5. Epithelia lacks vessel but innervated - Epithelia is dependent on underlying CT for supply of nutrients and gas Epithelia has nerve supplied Implications: - Regeneration 6. Epithelia are exposed to hostile environment - Skin: 45 days Intestinal lining: 5 days Example of regeneration - Epithelia Page 7
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Physical protection 1. Multiple layers of cells + strong intercellular attachment - Controlled permeability 2. Not skin - Example: vowels of small intestine for molecular transport - Molecules crossing apical & basal membrane Transcellular transport - Movement of molecules between cells Paracellular transport - Sensation 3. Touch, vision, hearing.
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This note was uploaded on 06/21/2011 for the course ANATOMY ana300y1 taught by Professor Wiley during the Fall '09 term at University of Toronto.

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Epithelia - Epithelia 09/14 ~ 1:25 PM Epithelia Page 1...

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