Vessels & Blood - Vessels & Blood O ctober 8,...

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Vessels & Blood October 8, 2010 9:16 AM Vessels & Blood Page 1
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Blood is always within blood vessel Pushing blood through 2 separate vascular system Circulation through the lung Arteries defined by the direction of blood flow Systemic circulation carries only oxygenated blood (regardless oxygenated or deoxygenated) Cells associated with capillaries Vessels & Blood Page 2
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Lease permeable and most common Tight junctions block paracellular molecular transport. Therefore, molecules should be transported through endothelial cells Endocytosis + Exocytosis Transcytosis --> process by which vesicles are formed on one phase of endothelial cell and move aside and contents released on different endothelial cell "Continuous capillary" Not as restricted as continuous capillary due to the pores ("fenestrations"). This allows rapid exchange of large molecules (i.e. small proteins, peptides, etc.), moving down concentration gradient. i.e. Endocrine tissue (chemical signalling) Found in places that requires rapid molecule exchange "Fenestrated capillary" Leakiest and not common Large pores, vessels large in diameter (reduces resistance to blood flow), BM is discontinuous (gases present) Rapid exchange of solute, exposure to antigen Blood vessels that are not restrictive "Sinusoid" i.e. lung, bone marrow, spleen, lymph note, Found in where blood is processed They interact with each other, between organs & dynamic. To optimize gas exchange in tissue. Collateral --> 2 vessels arranged in parallel (illustrated in the picture) Brain, heart, kidney Collateral flow acts as a back-up in case one fails to deliver sufficient blood supply. Metarterioles --> entrance to arteriole running to the vein Tight & closed --> increase the resistance to the blood flow through capillary. Instead, blood
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Vessels & Blood - Vessels & Blood O ctober 8,...

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