lect20sample - 1 2 3 4 5 6 7 8 9 101112 131415 161718...

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6. Using the following DNA sequence, consider each of the following cases separately. Use the chart below to determine which of the amino acids corresponds to each codon. 1 2 3 4 5 6 7 8 9 101112 131415 161718 192021 222324 252627 T T G A T A A A A A T G T T T T T G A G G T C C A T T Leu Ile Lys Met Phe Leu Arg Ser Ile First Position Second Position Third Position U C A G Phe Ser Tyr Cys U U Phe Ser Tyr Cys C Leu Ser Stop Stop A Leu Ser Stop Trp G Leu Pro His Arg U C Leu Pro His Arg C Leu Pro Gln Arg A Leu Pro Gln Arg G Ile Thr Asn Ser U A Ile Thr Asn Ser C Ile Thr Lys Arg A Met Thr Lys Arg G Val Ala Asp Gly U G Val Ala Asp Gly C Val Ala Glu Gly A Val Ala Glu Gly G a. What type(s) of mutation results from a deletion of nucleotide 9? Please give the sequence of the resulting protein. b. What type(s) of mutation results from a transition at position 19? How is the protein sequence altered? Name a chemical that is likely to produce such a change. Answers on next page
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6. Using the following DNA sequence, consider each of the following cases separately. Use the chart below to determine which of the amino acids corresponds to each codon.
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Unformatted text preview: 1 2 3 4 5 6 7 8 9 101112 131415 161718 192021 222324 252627 T T G A T A A A A A T G T T T T T G A G G T C C A T T Leu Ile Lys Met Phe Leu Arg Ser Ile First Position Second Position Third Position U C A G Phe Ser Tyr Cys U U Phe Ser Tyr Cys C Leu Ser Stop Stop A Leu Ser Stop Trp G Leu Pro His Arg U C Leu Pro His Arg C Leu Pro Gln Arg A Leu Pro Gln Arg G Ile Thr Asn Ser U A Ile Thr Asn Ser C Ile Thr Lys Arg A Met Thr Lys Arg G Val Ala Asp Gly U G Val Ala Asp Gly C Val Ala Glu Gly A Val Ala Glu Gly G a. What type(s) of mutation results from a deletion of nucleotide 9? Please give the sequence of the resulting protein. b. What type(s) of mutation results from a transition at position 19? How is the protein sequence altered? Name a chemical that is likely to produce such a change. frameshift Leu-Ile-Lys-Cys-Phe (Stop) Missense, Gly replaces Arg, 5-bromouracil or 2-aminopurine...
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This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

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lect20sample - 1 2 3 4 5 6 7 8 9 101112 131415 161718...

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