reviewfinal - Sample problems for final exam population...

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Sample problems for final exam – population genetics, etc. (not to be turned in, won’t be graded,  answers are on last page of this handout) 1.  Huntington’s chorea causes neurodegeneration and ultimately death. Onset of symptoms is usually  between the ages of 30 and 50. Huntington’s is inherited as an autosomal dominant. The frequency of  Huntington’s is approximately 1/20,000. Assume the population meets the criteria for Hardy-Weinberg,  and that there are only two alleles of the Huntington’s gene,  H  (the allele responsible for the disorder)  and  h A.  Calculate the frequency of  H  ( H  = mutant allele) in the population. B.  Calculate the frequency of  h  (where  h  refers to the wild-type allele).  C.  Calculate the frequency of homozygous wild type, heterozygotes and homozygous mutant within the  population. 2.  Patterning of the anterior-posterior body axis in  Drosophila  involves a series of protein interactions,  where early acting proteins regulate the expression of subsequent proteins. 
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reviewfinal - Sample problems for final exam population...

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