Lecture 13-07web

Lecture 13-07web - L312/Spring 2007 Lecture 13 Drummond Feb...

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Unformatted text preview: L312/Spring 2007 Lecture 13 Drummond Feb 22 For today: Focus on Chapter 17, 574-591: Cytoskeletal elements see also Chapter 4 pages 134-135, 121-125 on protein structure ast time: Focus on movement of materials by vesicular transport a) proteins can be concentrated INSIDE vesicles b) proteins inserted INTO membranes can be moved to other sites PM proteins synthesized in ERm and moved through Golgi c) Golgi has two faces; cis faces ER (entry), trans faces PM infer: directional movement through Golgi enter and leave via transport vesicles protein modification, packaging here d) clathrin (and Cop I and Cop II) mediate vesicular budding snares (v (vesicular) and t (target)) mediate targeting oday: Brief review of clathrin mechanism (vesicular transport from Golgi to PM) Begin cytoskeletal (structural) elements in the cell focus on: intermediate filaments (later actin and microtubules) How are modified ER proteins exported to other cellular organelles (and to the plasma membrane?) Remember where lipids are made!!! How is a specific protein or group of proteins concentrated and delivered to a membrane target?How is a specific protein or group of proteins concentrated and delivered to a membrane target?...
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This note was uploaded on 07/02/2011 for the course BIO-L 312 taught by Professor Drummond during the Fall '07 term at Indiana.

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Lecture 13-07web - L312/Spring 2007 Lecture 13 Drummond Feb...

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