Lecture 24-07 web - L312/Spring 2007 r today Lecture 24...

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L312/Spring 2007 Lecture 24 Drummond April 17 or today: Finish Chapter 21 Stem cells and cell differentiation Third exam Thursday, April 19th Review sessions: Today/tomorrow? Old: Focus on connections between cells (mostly epithelial layers (tissue)) tight junctions claudins and occludins adherens junctions actin bundles connected by cadherins desmosomes intermediate filaments (keratins) con. by cadherins hemidesmosomes keratins connected to integrins con. to basal lamina gap junctions connexins span four membranes to form pore Formation of tubules: constriction of actin rings in individual cells connected by adherens junctions in a layer of tissues New: How tissues are maintained and replaced? where do new cells (and many cancers) come from? what maintains cells in a differentiated state in a tissue? what are stem cells, and why are they important? what kinds of cell types are likely to initiate tumorigenesis?
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How are epithelial cells interconnected?
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