Lecture 25-07 web

Lecture 25-07 web - L312/Spring 2007 r today: Lecture 25...

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L312/Spring 2007 Lecture 25 Drummond April 24 or today: Last of Chapter 21: Cancer: p 726-end Last set of study questions (on final as multiple choice)--post shortly Exams back by Thursday! All materials outside my office after that ast time: How tissues are maintained and replaced Maintenance: signals sent out (secreted) from neighboring cells specific adhesion molecules (cadherins) within tissue epigenetic modifications preserve tissue ‘memory’ (DNA methylation/histone modifications) Regeneration: stem cells replace all the cell types in a tissue undifferentiated, self-regenerate often protected physically from environmental skin cells generated from basal level and move ‘up’ gut cells generated in crypts and migrate ‘up’ differentiation controlled by external signaling molecules his time: the progression of proliferative cells to cancers
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Where do new tissue cells come from? Which cells may become cancerous? Take home…
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Tissue renewal in the gut--where are new cells ‘born’
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(what must happen for cells to escape their normal role?)
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Lecture 25-07 web - L312/Spring 2007 r today: Lecture 25...

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