7. When Things Go Wrong

7. When Things Go Wrong - So What Happens When Things Go...

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So What Happens When Things Go Wrong?
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Nondisjunction One pair of chromosomes fails to separate during meiosis
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Trisomy Zygote ends up with 3 chromosomes instead of 2 for a given pair of chromosome.
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Normal Male
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Normal Female
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Trisomy 21 Down Syndrome
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Down Syndrome Large tongue Flat face Single crease across palm Slanted eyes Mental retardation Some are not
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Maternal Age & Down Syndrome
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Trisomy 18 Edward Syndrome
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Edward Syndrome Heart defects Displaced liver Abnormal hands Low-set ears Severe retardation 98% abort Lifespan < 1 year
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Trisomy 13 Patau Syndrome
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Patau Syndrome Cleft lip and palate polydactylism Defects Heart Brain Kidney Most abort Live span < 1 month
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Klinefelter Syndrome
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Klinefelter Syndrome Breast development Small testes Sterile Low intelligence Not retarded Klinefelter Website
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This note was uploaded on 06/23/2011 for the course BIO 111 taught by Professor Tatum/parker during the Spring '11 term at St. Xavier.

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7. When Things Go Wrong - So What Happens When Things Go...

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