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exam2-09key - name student ID Genetics L311 exam 2...

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name:_______________________ student ID:_____________________ Genetics L311 exam 2 October 23, 2009 Directions: Please read each question carefully. Answer questions as concisely as possible. Excessively long answers, particularly if they include any inaccuracies, may result in deduction of points. You may use the back of the pages as work sheets, but please write your answer in the space allotted. However, you must show all your work. Clearly define your genetic symbols. We will not make guesses as to what a particular symbol is intended to mean. Also, don’t assume that strains are true-breeding unless this is stated in the question. Finally, show all your work. Good luck. page 2 _______ (20 points possible) page 3 _______ (26 points possible) page 4 _______ (18 points possible) page 5 _______ (20 points possible) page 6 (16 points possible) total _______ (of 100 points possible) 1
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name:_______________________ student ID:_____________________ 1. Short answers (2 points each, 20 points total) A. Densely staining, compact and relatively transcriptionally inactive regions of chromosomes are referred to as heterochromatin . B. The culture of “normal”, untransformed somatic cells is called primary culture . C. A change in DNA sequence that converts a mutation back to wild type sequence is called a(n) reversion . D. An example of a(n) transition mutation would be substitution of a G for an A. E. Genetic anticipation is the occurrence of a disorder at progressively younger ages in subsequent generations. F. The specialized structures that protect the ends of chromosomes from becoming shortened as a consequence of replication are called telomeres . G. The site on the chromosome that a gene occupies is referred to as a(n) locus . For the following, please provide a brief definition of the term given: H. null mutation: Completely eliminates gene function I. epistasis: Phenotypic expression from one locus depends on the genotype at another. J. holocentric: Chromosome in which centromere forms along its entire length. 2
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name:_______________________ student ID:_____________________ 2. In L. weaverae , a newly discovered insect, you are trying to map three linked genes. Mutations in l , causes little wings to form, b causes blue eyes and s causes short legs. Each of these mutations is recessive. A triple heterozygote is crossed with homozygous recessive to produce
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