final-09key - name:_ student ID:_ Genetics L311 final exam...

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name:_______________________ student ID:_____________________ Genetics L311 final exam December 18, 2009 Directions: Please read each question carefully. Answer questions as concisely as possible. Excessively long answers, particularly if they include any inaccuracies, may result in deduction of points. You may use the back of the pages as work sheets, but please write your answer in the space allotted. However, you must show all your work. Clearly define your genetic symbols. We will not make guesses as to what a particular symbol is intended to mean. Also, don’t assume that strains are true-breeding unless this is stated in the question. Finally, show all your work. Good luck. page 2 (30 points possible) page 3 (34 points possible) page 4 (15 points possible) page 5 (28 points possible) page 6 (20 points possible) page 7 (31 points possible) page 8 (26 points possible) page 9 (16 points possible) total (of 200 points possible) 1. Short answers (2 pts each, for total of 30 pts) 1
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name:_______________________ student ID:_____________________ A . Pleiotropy is when a mutation in a single gene affects many traits. B. Compounds that induce different cell fates depending on their levels are called morphogens . C. The specialized structures that protect the ends of chromosomes from becoming shortened as a consequence of replication are called telomeres . D. The pair rule genes specify the development of alternating segments during Drosophila development. (I’m looking for the class of genes, not examples of members of this class.) E. Linkage is the tendency for genes located on the same chromosome to be inherited together. F. Replacement of one body part with another is homeosis . G. Damaged or defective cells can be induced to die by activating a process known as apoptosis . H. The complete set of genetic information within all of the individuals in a population is the gene pool . I. A change in DNA sequence that converts a mutation back to wild type sequence is called a(n) reversion . J. Several cells that have the same developmental potential (i.e. can adopt the same fate) constitute a(n) equivalence group . K. Locus is the physical location of a gene on a chromosome. L. Synapsis is the pairing of homologous chromosomes during meiosis. Please provide a brief definition of each of the following: M. trisomy: Diploid cell with one extra chromosome. N. oncogene: Cellular gene that has been mutated in such a way as to promote cancer. O. prion: An infectious proteinaceous particle that causes disease by interacting with and promoting the misfolding of an endogenous protein. 2. Hurler syndrome is an autosomal recessive disorder that affects about 1/100,000 individuals in North America. It is characterized by progressive mental retardation, dwarfism and “gargoyle-like” facial features.
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This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

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final-09key - name:_ student ID:_ Genetics L311 final exam...

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