lec07 - Lecture 7 Pedigree analysis I. Pedigree A. what is...

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Picture 18 Lecture 7 – Pedigree analysis   I. Pedigree A. what is it? - diagram of familial relationship and transmission of traits.  B. how is it useful?    C. In general, genetic disorders are very rare. D. 4 primary patterns of inheritance 1. autosomal recessive 2. autosomal dominant 3. X-linked recessive 4. X-linked dominant 5. Y-linked E. Commonly used symbols. 1
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Picture 16 II. Patterns of inheritance A. autosomal recessive 1. Clues to pattern: a. Unaffected parents can have affected offspring. b. Both sexes affected equally. c. Tends to skip generations. d. Two effected parents produce all effected children. e. One effected and one unaffected parent usually produce all unaffected. f. Trait is more frequent among offspring of related parents. 2. Examples: 2
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Picture 6 a. albinism b. cystic fibrosis c. sickle cell anemia d. phenylketonuria e. methylmalonic acidemia B. autosomal dominant
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This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

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lec07 - Lecture 7 Pedigree analysis I. Pedigree A. what is...

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