lec08 - blood protein HbA/HbA viable not sickled HbA made...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Picture 20 Picture 28 blood protein Hb A /Hb A viable not sickled Hb A made Hb A /Hb S viable partly sickled both Hb A S Hb S /Hb S lethal all sickled Hb S made Lecture 8 – Genetic analysis/Modifications to Mendelian ratios I. Gene products may not act independently A. pleiotropy –  eg. fly  white  gene B. many genes may affect single trait C. How can many genes affect one trait? - consider hypothetical pathway for red pigment production - many steps required to make  product - each step catalyzed by different enzyme (1, 2, 3……) - so, often, many genes are required to synthesize a single product II. Test for allelism Q. If many genes can contribute to single product, how do we know if 2 mutations causing same  phenotype are in same gene? A. We use a simple genetic test, called a complementation test 1. How does complementation test work?
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

Page1 / 9

lec08 - blood protein HbA/HbA viable not sickled HbA made...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online