lec12 - Lecture 12 Genetic mapping I. Genetic mapping A....

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Picture 12 Lecture 12 -  Genetic mapping I. Genetic mapping A. genetic map B. map unit –  1. map unit = 1/2(# crossovers between markers) 2. 1 map unit = 1% recombination expressed as map units or centiMorgans C. frequency proportional to distance between genes II. Two-factor mapping A. example 1 w +   = red eyes wm + / wm +  female X  w + m /Y male w  = white eyes     m +  = normal wings wm + / w + m wm + /Y m  = mini wings     226 wm + /Y 202 w + m /Y 102 wm /Y 114 w + m + /Y B. example 2 y  = yellow body  y + w / y + w  female X  yw + /Y male y+  = dark body     w  causes white eyes y + w / yw + y + w /Y w+  = red eyes     4292 y + w /Y 1
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Picture 15 4605 yw + /Y     86 y + w + /Y     44 yw /Y III. Double crossovers A. As distance between genes increases, probability of double crossovers increases P{double} = P{single} X P{single} B. Double crossovers between markers only detected if third gene is involved
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lec12 - Lecture 12 Genetic mapping I. Genetic mapping A....

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