lec19 - Lecture 19 Chromosome structure 2 I. centromere A....

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Unformatted text preview: Lecture 19 Chromosome structure 2 I. centromere A. Region of chromosome that associates with spindle fibers Picture 14 B. Terms 1. kinetochore 2. two types of centromeres: holocentric localized centromere C. chromosomes are characterized by centromere location 1 Picture 13 II. telomere 2 Picture 15 A. First, brief review of replication B. What would happen during replication at ends of chromosomes? Picture 16 3 C. How is the "end" problem dealt with? 1. bacteria and some viruses: 2. some linear viruses: 3. eukaryotic chromsomes: Picture 10 D. What's a telomere? 1. 2. 4 E. how do telomeres solve the "end" problem? Picture 12 F. Implications of telomeres on human health 1. aging: telomeres not made in some cells 2. cancer: some cancer cells reactivate telomerase expression 5 ...
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This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

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lec19 - Lecture 19 Chromosome structure 2 I. centromere A....

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